Proton Channel Activity of Influenza A Virus Matrix Protein 2 Contributes to Autophagy Arrest
نویسندگان
چکیده
منابع مشابه
Proton and cation transport activity of the M2 proton channel from influenza A virus.
The M2 protein is a small, single-span transmembrane (TM) protein from the influenza A virus. This virus enters cells via endosomes; as the endosomes mature and become more acidic M2 facilitates proton transport into the viral interior, thereby disrupting matrix protein/RNA interactions required for infectivity. A mystery has been how protons can accumulate in the viral interior without develop...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2016
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.00576-15